Researcher Wins Prestigious International Award
Mone Zaidi, MD, PhD, Director of the Center for Translational Medicine and Pharmacology and Professor of Medicine, and Pharmacological Sciences, at the Icahn School of Medicine at Mount Sinai, has received the 2022 International Research Award from the Austrian Bone and Mineral Society, Austria’s largest medical society. The International Research Prize is the most coveted prize in bone and mineral research and is awarded every three years.
Since its inception in 1988, the International Research Prize has been awarded to individuals whose recent work in molecular, cellular, or materials science, or the pathophysiological or clinical aspects of bone and mineral metabolism, has resulted in new findings or concepts. .
An international jury independently selected Dr. Zaidi was the prize winner, and he was awarded EUR 7,500 ($8,000 USD) at Osteoporoseforum, the 30th The annual meeting of the Austrian Bone and Mineral Society, held in St. Wolfgang, Austria, June 23-25. Dr. The following Zaidi was featured during this conference.
- Oxytocin regulates body composition. Proceedings of the National Academy of Sciences 116: 26808-26815.
- First-in-class humanized FSH-blocking antibody targets bone and fat. Proceedings of the National Academy of Sciences 117: 28971-28979.
- FSH blockade improves cognition in mice with Alzheimer’s disease. Nature 603: 470-476.
“It has been a truly humbling experience to be awarded this award and join such a small group of renowned people in my field—something I could not have accomplished without the extremely talented teachers and trainees and distinguished collaborators who have had the honor to work with same with me. all this time,” said Dr. Zaidi.
Dr. Zaidi has made groundbreaking discoveries about the mechanisms of bone homeostasis in health and disease. These studies, spanning more than 30 years, included the first descriptions of calcium sensing in osteoclasts and the discovery that locally released nitric oxide acts to suppress bone cells. In 2003, Dr. Zaidi published the first evidence for the pituitary-bone axis, a breakthrough in physiology in which pituitary hormones can affect the skeleton directly. In a recent groundbreaking paper in Nature, he found that inhibiting follicle-stimulating hormone (FSH) not only increases bone mass, but also reduces body fat and neurodegeneration—essentially laying a solid foundation for a single anti-FSH agent to treat osteoporosis, obesity, and Alzheimer’s disease.
The corpus of work related to FSH with body fat was selected by Nature Medicine as one of the eight “Leading Advances” in biomedicine for 2017. Zaidi has been funded continuously by the National Institutes of Health (NIH). He has also chaired several Sections of Studies for the NIH and the Department of Veterans Affairs. He served as President of the Interurban Clinical Club and was elected to the Association of American Physicians, the Society of Practitioners (the oldest medical society in the United States) and the Association of Professors of Medicine. Zaidi is a Master of the American College of Physicians, received the Harrington Scholar-Innovator Award, was elected a Fellow of the American Association of Advancement of Science, and is the recipient of three honorary doctorates.
“Dr. Zaidi is an outstanding researcher who has made pioneering discoveries about the mechanisms of musculoskeletal homeostasis in health and disease throughout his career,” says Eric J. Nestler, MD, PhD, Nash Family Professor of Neuroscience, Director of The Friedman Brain Institute, and Mount Sinai Icahn Dean for Academics. , and Chief Scientific Officer of the Mount Sinai Health System. “I congratulate Dr. Zaidi for having received one of the most prestigious awards in his field and we are delighted that he is recognized by the largest medical society in Austria.”
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