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People often think that early embryos are fragile and need support. However, in the early stages of development, it has the power to feed the future placenta and command the uterus for nesting. Using the ‘blastoid’, an in vitro embryo model formed with stem cells, Nicolas Rivron’s Lab at IMBA demonstrated that the earliest molecular signals that induce placental development and prepare the uterus come from the embryo itself. The findings, now published in Cell Stem Cell, could contribute to a better understanding of human fertility. Who took care of whom in early life? The placenta and uterus nourish and protect the fetus. But the situation at an early stage of development, when the blastocyst is still afloat in the uterus, is so far unclear. Now, Nicolas Rivron’s group of researchers at IMBA (Institute of Molecular Biotechnology of the Austrian Academy of Sciences) discovered the basic principles of early development using blastoids. The blastoid is an in ...

When rideshare giant Uber first launched in Australia in 2012, it was greeted with enthusiasm from customers who were tired of waiting long and not arriving from taxis. Key points: Customers say Uber cancellations have increased over the past few months Uber says it’s not the fault of the drivers, who are struggling amid rising fuel prices Demand rises as “Queenslanders returns to pre-pandemic travel patterns” Ten years later, frustration is growing among Uber customers with very similar complaints. Uber drivers say rising fuel costs are to blame, while the company cites increased demand as travelers revert to pre-pandemic habits. Leigh Macey is a regular Uber driver in Cairns, but she says the increase in cancellations keeps her from going out for a drink. “It’s like a struggle to try and get home,” he said. “When you go out and want to go home, you want to go home – not two hours later. “If you get a driver who actually shows up wi...