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Coronavirus disease 2019 (COVID-19) is a viral respiratory tract infection that is responsible for various thrombotic events in major blood vessels in the human body, especially deep vein thrombosis (DVT) and pulmonary embolism. [1]. These thromboembolic events are thought to arise from an immune and pro-inflammatory response that results in the production of procoagulation factors that are responsible for vascular injury. Despite the predominant venous etiology, rare reports now implicate COVID-19 in adverse arterial events such as arterial thrombosis that can lead to acute limb ischemia (ALI). [1]. ALI is an emergent vascular event that results in decreased limb blood flow and subsequent tissue hypoperfusion [2]. This article was previously presented as a poster at Michigan State University State University Emergency Medicine Resident Case Report Poster Day on February 16, 2022, and at the Henry Ford Health Systems Medical Education Research Forum on April 1, 2021. A 69-year-old w...

Background and purpose Thrombosis is one of the significant challenges associated with cardiovascular disease and the leading cause of death globally. This study aims to determine the monthly and overall mortality rates by sex and age group in hospitalized patients with coronavirus disease 2019 (COVID-19) and the prevalence of deep vein thrombosis (DVT) in these patients. We also investigated whether the P.1 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects DVT. Method We determined the overall prevalence of COVID-19 per gender, age, and monthly mortality using hospital data at the São José do Rio Preto School of Medicine, state of São Paulo, Brazil. Data of COVID-19 patients with DVT as determined by echo-Doppler ultrasound (EDU) were analyzed considering two time periods (before and after the onset of the predominance of the SARS-CoV-2 P. Patients with COVID-19 but without DVT comprised the control group. The first period is from March 2020 to Febru...