Scientists Develop New Electrochemical/fluorescent Dual-mode Biosensor
Researchers at the Suzhou Institute of Biomedical Engineering and Technology (SIBET) of the Chinese Academy of Sciences recently proposed a structured DNA assembly strategy and developed an electrochemical/fluorescent dual-mode biosensor for circulating tumor DNA based on methylene blue. and red emission carbon nanodots. The new sensors, combining the characteristics of electrochemical and fluorescent sensors, whose signal sources and construction methods are usually very different, according to the researchers. Electrochemical sensor is a qualitative or quantitative method based on the correlation between targets caused by changes in electrical signals and concentrations or other physical parameters. Fluorescence sensor is a qualitative or quantitative detection method by transmitting a specific combination of target elements and introduction to the fluorescence element, causing a change in the fluorescence intensity or emission wavelength. “Integrating two technologies for synchrono