Opportunities in Melanoma Diagnosis Using Surface Enhanced Raman Scattering Biosensors
In a recent study published in Journal of Physical Chemistry C , researchers demonstrate an approach to detect tyrosinase activity (TYR), an important biomarker for melanoma diagnosis, with the help of an unprecedented surface-enhanced Raman scattering biosensor. Study: Surface Enhanced Raman Scattering Biosensor Based on Self-Assembled Gold Nanorod Array for Fast and Sensitive Tyrosinase Detection . Image Credit: Africa Studio/Shutterstock.com The surface-enhanced Raman scattering biosensor, fabricated on a glass chip, was developed on an array of dopamine-operated Au nanorods (Au NR) that function as capture substrates and 4-mercaptophenylboronic acid (4-MPBA) altered silver nanoparticles (Ag NPs). ) formed a surface-enhanced Raman scattering biosensor probe. Since detecting TYR activity in biological samples is essential for clinical melanoma diagnosis, the proposed approach with various advantages of sensitivity, portability, and reproducibility could be useful for melanoma d