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Super-resolution microscopy allows fluorescence images of cells, organelles and molecular complexes to be obtained with unprecedented spatial resolution. However, this resolution is not sufficient to resolve proteins as small as a few nanometers and their interactions with other molecules or the architecture of protein complexes. This prevents, for example, the study of the molecular interactions of neurons in learning and memory processes. Overcome dynamic resolution limit Developed by the research groups of Prof Markus Sauer (Rudolf Virchow Center and Biocenter) and Dr Gerti Beliu (Rudolf Virchow Center) at the University of Würzburg, the new photoswitching fingerprint analysis enables optical imaging of dynamic interactions with other molecules in cells. “To date, no method has reliably enabled structural optical resolution in cells in the sub-10 nm range. By elucidating the underlying cause of this barrier, we have succeeded for the first time, in combination with a new dir...

Super-resolution microscopy allows fluorescence images of cells, organelles and molecular complexes to be obtained with unprecedented spatial resolution. However, this resolution is not sufficient to resolve proteins as small as a few nanometers and their interactions with other molecules or the architecture of protein complexes. This prevents, for example, the study of the molecular interactions of neurons in learning and memory processes. Overcome dynamic resolution limit Developed by the research groups of Prof Markus Sauer (Rudolf Virchow Center and Biocenter) and Dr Gerti Beliu (Rudolf Virchow Center) at the University of Würzburg, the new photoswitching fingerprint analysis enables optical imaging of dynamic interactions with other molecules in cells. “Until now, there was no reliable method of enabling structural optical resolution in cells in the sub-10 nm range. By elucidating the underlying cause of this barrier, we have succeeded for the first time, in combination with a...

A study recently published in Chemical analysis proposed a strategy for optical detection of several bacterial species based on the optical properties of the nanohybrid structure of polymer-coated metal nanoparticles. Study: Simultaneous Optical Detection of Several Bacterial Species Using Nanometer-Scale Metal-Organic Hybrids . Image Credit: Yurchanka Siarhei/Shutterstock.com Rapid detection of bacteria is critical because of the rise of antibiotic-resistant microbes, the global food trade, and their applications in pharmaceuticals, bioremediation, and food production. The optical detection technique has piqued the curiosity of researchers because of its potential for rapid, high-throughput, non-destructive, and amplification-free identification. Development of Bacterial Detection Techniques Several species of bacteria are useful for improving safety and quality of life in medicine, food production and energy; however, some bacteria are harmful. Bacterial identification tests c...

A study recently published in Chemical analysis proposed a strategy for optical detection of several bacterial species based on the optical properties of the nanohybrid structure of polymer-coated metal nanoparticles. Study: Simultaneous Optical Detection of Several Bacterial Species Using Nanometer-Scale Metal-Organic Hybrids . Image Credit: Yurchanka Siarhei/Shutterstock.com Rapid detection of bacteria is critical because of the rise of antibiotic-resistant microbes, the global food trade, and their applications in pharmaceuticals, bioremediation, and food production. The optical detection technique has piqued the curiosity of researchers because of its potential for rapid, high-throughput, non-destructive, and amplification-free identification. Development of Bacterial Detection Techniques Several species of bacteria are useful for improving safety and quality of life in medicine, food production and energy; however, some bacteria are harmful. Bacterial identification tests c...

Research led by Monash University and RMIT in Melbourne have figured out how to create advanced photonic integrated circuits that build bridges between data superhighways, revolutionizing the connectivity of today’s optical chips and replacing bulky 3D optics with thin slices of silicon wafers. This development, published in the prestigious journal Nature Photonics has the ability to accelerate the global advancement of artificial intelligence and offers significant real-world applications such as: Safer driverless cars capable of instantly interpreting their surroundings Enable AI to diagnose medical conditions faster Makes natural language processing faster for apps like Google Homes, Alexa, and Siri. Smaller switch to reconfigure the optical network that carries our internet to get data where it is needed faster Whether it’s turning on the TV or keeping the satellites on track, photonics (the science of light) is changing the way we live. Photonic chips can turn large b...

Nature Photonics (2022). DOI: 10.1038/s41566-022-01020-z”> Nature Photonics (2022). DOI: 10.1038/s41566-022-01020-z” width=”800″ height=”530″/> Conceptual diagram of a self-calibrating integrated broadband PIC. Credit: Xingyuan Xu et al, Nature Photonics (2022). DOI: 10.1038/s41566-022-01020-z Research led by Monash and RMIT University in Melbourne has found a way to create advanced photonic integrated circuits that build bridges between data superhighways, revolutionizing the connectivity of today’s optical chips and replacing bulky 3D optics with thin slices of silicon wafers. This development, published in the journal Nature Photonics has the ability to accelerate the global advancement of artificial intelligence and offers significant real-world applications such as: Safer driverless cars capable of instantly interpreting their surroundings Enable AI to diagnose medical conditions faste...

The dark matter field of dark photons transforms into photons in a layered dielectric target. These photons are focused by the lens onto a small, low-noise SNSPD detector. The light emitted from the stack is approximately uniform except for a small region in the center where the mirror is absent. Credit: Chiles et al. Researchers at the National Institute of Standards and Technology (NIST), Massachusetts Institute of Technology (MIT) and the Perimeter Institute recently set new limits on dark photons, which are hypothetical particles and well-known candidates for dark matter. Their findings, presented in a paper published in Physical Review Letter This was achieved using the new superconducting nanowire single-photon detector (SNSPD) they developed. “There is close collaboration between our research groups at NIST and MIT, run by Dr. Sae Woo Nam and Prof. Karl Berggren, respectively,” Jeff Chiles, one of the researchers wh...