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Using innovative microscopy methods, scientists at The Picower Institute for Learning and Memory at MIT observed how nascent neurons struggle to reach their rightful places in a sophisticated human brain network model of Rett syndrome, yielding new insights into how developmental deficits are observed in humans. patient’s brain. with devastating interference may arise. Rett syndrome, which is characterized by symptoms including severe intellectual disability and impaired social behavior, is caused by a mutation in the MECP2 gene. To gain new insight into how mutations affect the early stages of human brain development, researchers in the lab of Mriganka Sur, Newton Professor of Neuroscience in MIT’s Department of Brain and Cognitive Sciences, grew 3D cell cultures called cerebral organoids, or miniature brains, using cells from humans. -people with the MECP2 mutation and compared them with identical cultures without the mutation. Then a team led by postdoc Murat Yildirim examined th

The small crustacean Idotea balthica facilitates the dispersal of male gametes and fertilization in the red alga Gracilaria gracilis. They use dense, branching red algae for cover and feed on microalgae that grow on their surface. Credit: © Wilfried Thomas @Station Biologique de Roscoff, CNRS, SU, Roscoff, France The important role of insects in pollinating flowering plants is well known, but marine animal-assisted algae fertilization has hitherto been considered non-existent. A team led by a CNRS researcher from the French-Chilean Evolutionary Biology and Ecology research unit at Roscoff Marine Station has discovered that tiny crustaceans known as idoteas contribute to the reproductive cycle of the red alga Gracilaria gracilis. The scientists’ findings were published in Science . They suggest that animal-mediated fertilization is much older than previously thought. Are marine animals involved in the reproduction cycle of algae, such as poll

When it comes to searching for asteroids, we have a blind spot. It may seem counterintuitive, but the asteroid’s most important discoveries are now being made at dusk, when astronomers can see up close to the horizon – and close to the sun – for what little is known. asteroids orbiting within the orbits of Earth, Venus and even Mercury. In perspective published in Science today, asteroid hunter Scott Sheppard of the Carnegie Institution of Science highlights the new “twilight telescope” surveys and the riches they are beginning to discover. It includes the first asteroid with an interior orbit to Venus and the one with the shortest known orbital period around the sun, both of which have been unearthed in the past two years. It also includes “city killers”, asteroids large enough that if they hit Earth the damage will be severe. “We’re doing a full survey looking for anything moving around the orbit of Venus, which is somewhere we haven’t surveyed very deeply in the past with anyth

Scientists have debunked the popular theory of how a woodpecker can repeatedly beat its beak against a tree at high speed without damaging its own brain. The researchers analyzed high-speed video of three woodpecker species — the stacked woodpecker, the black woodpecker, and the great spotted woodpecker. They found their skulls did not act like shock-absorbing helmets as previously thought, but more like rigid metal hammers. In fact, their calculations showed that any shock absorbers would hinder the woodpecker’s pecking ability. Woodpeckers quickly drill into trees to extract insects deep in the wood with their long tongues. An international team of researchers has analyzed high-speed video of three woodpecker species. Here is a sequence of frames from a high-speed video of a woodpecker pecking (Dryocopus pileatus) Photo of a black woodpecker (Dryocopus martius) filmed in a study in Alpenzoo Innbruck, Austria HAMMER OR HELMET? Scientists have long wondered how woodpecker

New research led by Curtin University has pinpointed the home of the oldest and most famous Martian meteorite for the first time, offering important geological clues to Mars’ early origins. Using a multidisciplinary approach involving machine learning algorithms, new research – published today in Nature Communication – identified a specific crater on Mars that ejected the so-called ‘Black Beauty’ meteorite, weighing 320 grams, and paired rock, which was first reported to have been found in northern Africa in 2011. Researchers have named a particular Martian crater after the town of Karratha in the Pilbara, located more than 1500km north of Perth in Western Australia, which is home to one of the oldest terrestrial rocks. Lead author Dr Anthony Lagain, from Curtin’s Space Science and Technology Center in the School of Earth and Planetary Sciences, said the exciting discovery offered previously unknown details about the Mars meteorite NWA 7034, known as ‘Black Beauty’, which is widely st

Washington [US], July 9 (ANI): Exposure to copper in the environment and the protein alpha-synuclein in the human brain may play an important role in the pathogenesis of Parkinson’s disease. The researchers were able to show how the protein takes on an unusual shape when exposed to large amounts of copper ions. These findings could help develop new strategies for the treatment of neurodegenerative diseases. The causes of Parkinson’s disease are not fully understood. Long before the onset of characteristic muscle tremors, the appearance of faulty proteins in the brain can be the first sign. Researchers at Empa and the University of Limerick in Ireland have now taken a closer look at the abnormal shape of these alpha-synucleins in the form of a protein ring. By doing so, they were also able to visualize at the nanoscale the relationship with environmental pollution by copper. It highlights the development of neurodegenerative diseases and the role of biometals in the disease proces

image: Utibe Essien, MD, MPH see again Credit: University of Pittsburgh PITTSBURGH, July 7, 2022 – While patients with diabetes on the Medicare Advantage plan are more likely to receive preventative care, they are less likely to be prescribed new, more expensive drugs and more likely to have high blood pressure and poorer blood glucose control than patients on the Cost plan Medicare-For-Services, according to a new study led by physician-scientists at the University of Pittsburgh School of Medicine. The study, published today in Diabetes Treatment, raised the red flag that – despite increasing access to preventative care – rapid growth in Medicare Advantage registrants could signal a trend toward poorer health outcomes and gaps in care when compared to their Medicare Fee-For-Service counterparts. “Preventive care is not enough to prevent patients from utilizing the healthcare system in the future,” said lead author Utibe Essien