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Scientists uncover mechanisms that shape the distribution of centromeres

Since the 1800s, scientists have noted the configuration of the centromere, a special region of chromosomes essential for cell division, in the nucleus. To date, however, the determination mechanism and biological significance of the centromere distribution is poorly understood. A team led by researchers from the University of Tokyo and their collaborators recently proposed a two-step regulatory mechanism that forms the distribution of centromeres. Their findings also suggest that the configuration of the centromere in the nucleus plays a role in maintaining genome integrity. The results were published in Natural Plants . During the process of cell division, special chromosomal domains called centromeres are pulled to opposite ends of the cell. Once the cell division is complete and the cell nucleus is built, the centromeres are distributed spatially in the nucleus. If the distribution of the centromeres drawn to the two poles remained unchanged, the cell nucleus would have centro

Uncover the physical mechanics behind the micro-swimmer's movement

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Chemical trace visualization. (A) Schematic of the experimental setup for fluorescent microscopy of charged micelle traces. CB15 droplet diameter a drop =50 was injected into a quasi-2D microfluidic cell (height = 50 m) and observed using a bright-field or fluorescent microscope. (B) A fluorescence micrograph of a chemical trace droplet, with the surfactant concentration increased to 15% by weight to increase the visibility of the trace (increased solubility level). (C) Enlarged view of B. (D) Schematic of the drip propulsion mechanism. Black arrows indicate the direction of movement. (E) The flow field generated by the Marangoni flow at the droplet interface visualized by the streak lines of a 0.5 m fluorescent tracer colloid (droplet reference frame). (F) Time evolution of fluorescent intensity (in arbitrary units [a.u.]) profile along AA (Inset) superimposed with Gaussian fit (5 wt% surfactant concentration). (G) Peak intensity vs. time. The ze

The Southern Hemisphere's first deep sky telescope seeks to uncover the secrets of the universe

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The Southern Hemisphere’s first deep-sky telescope is poised to shed new light in some of the darkest parts of the universe, as it begins its survey of western New South Wales. Developed by Macquarie University, the Hunter Telescope has been unveiled at the Siding Spring Observatory, nestled among the mountains of the Warrumbungle Range near Coonabarabran. Project team member Sarah Caddy says the Huntsman design allows for highly specialized research into the formation and evolution of galaxies. “When we look for very dim objects, objects with low surface brightness, we want to collect as much light as possible,” he said. Built almost entirely from ready-to-use technology, the Hunter’s “eyes” are Canon’s 10 telephoto lenses. ( ABC Western Plains: Nic Healey ) “With traditional mirror-based telescopes, they can scatter light into parts of the field of view that we don’t want … that makes it very difficult to find very dim things around galaxies. “What we do is we have 10 lenses, all l