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Scientists uncover mechanisms that shape the distribution of centromeres

Since the 1800s, scientists have noted the configuration of the centromere, a special region of chromosomes essential for cell division, in the nucleus. To date, however, the determination mechanism and biological significance of the centromere distribution is poorly understood. A team led by researchers from the University of Tokyo and their collaborators recently proposed a two-step regulatory mechanism that forms the distribution of centromeres. Their findings also suggest that the configuration of the centromere in the nucleus plays a role in maintaining genome integrity. The results were published in Natural Plants . During the process of cell division, special chromosomal domains called centromeres are pulled to opposite ends of the cell. Once the cell division is complete and the cell nucleus is built, the centromeres are distributed spatially in the nucleus. If the distribution of the centromeres drawn to the two poles remained unchanged, the cell nucleus would have centro

New model of fluid distribution in the Cascadia Subduction Zone helps understanding seismic activity

A new three-dimensional model of the fluid stored deep within the Earth’s crust along the Cascadia Subduction Zone provides new insights into how the accumulation and release of such fluid can affect seismic activity in the region. The liquid collects near but does not penetrate the thickened section of crust known as Siletzia lying beneath much of western Oregon and Washington. The pressure associated with this fluid could be a factor in the seismic phenomenon known as episodic tremor and slip, or ETS, said Gary Egbert, an electromagnetic geophysicist at Oregon State’s College of Earth, Ocean, and Atmospheric Sciences and lead author of the new paper. detail the findings. Episodic tremors and slips are fault behaviors that include localized non-volcanic vibrations and slow slip events that may occur over hours or days. It occurs throughout the Cascadia Subduction Zone, from northern California to British Columbia, but is less frequent and intense under the Siletzia central core, wh