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Coronavirus disease 2019 (COVID-19) is a viral respiratory tract infection that is responsible for various thrombotic events in major blood vessels in the human body, especially deep vein thrombosis (DVT) and pulmonary embolism. [1]. These thromboembolic events are thought to arise from an immune and pro-inflammatory response that results in the production of procoagulation factors that are responsible for vascular injury. Despite the predominant venous etiology, rare reports now implicate COVID-19 in adverse arterial events such as arterial thrombosis that can lead to acute limb ischemia (ALI). [1]. ALI is an emergent vascular event that results in decreased limb blood flow and subsequent tissue hypoperfusion [2]. This article was previously presented as a poster at Michigan State University State University Emergency Medicine Resident Case Report Poster Day on February 16, 2022, and at the Henry Ford Health Systems Medical Education Research Forum on April 1, 2021. A 69-year-old w...

Cross section of healthy skin, showing layers of skin (red), the normal microbiome of skin bacteria (green) and several types of immune cells (purple). In the skin affected by colitis, the bacteria remain the same, but the number of immune cells is greater, creating inflammation. Image by Scharschmidt Lab. A new study by UC San Francisco researchers reveals how intestinal inflammation can irritate not only the digestive system, but the skin as well. It’s a story in which the main players are specialized immune cells and the community of bacteria – called the microbiome – that resides in the gut and skin. Scientists are becoming increasingly aware that disruptions to the gut microbiome can affect other parts of the body. These changes have been linked to an increased risk of diseases such as asthma, rheumatoid arthritis, multiple sclerosis. In a study published May 31, 2022 in Cell Reports, a team of researchers investigated how colitis, or chronic inflammation of the colon, ca...

Immunotherapy, such as immune checkpoint inhibitors, has changed the treatment of advanced cancers. Unlike chemotherapy which kills cancer cells, these drugs help the immune system to find and destroy the cancer cells themselves. Unfortunately, only a subset of patients respond to immune checkpoint inhibitors in the long term; and these treatments can be expensive and with side effects. Researchers have developed a two-step approach using whole-exome sequencing to target genes and pathways that predict whether cancer patients will respond to immunotherapy. Studies published in Nature Communication and conducted by researchers at New York University, Weill Cornell Medicine, and the New York Genome Center, illustrates how using whole-exome sequencing can better predict treatment response than current laboratory tests. “Can we better predict who will benefit from immunotherapy? Scientists have developed a variety of biomarkers that help anticipate immunotherapy treatment respons...

image: Utibe Essien, MD, MPH see again Credit: University of Pittsburgh PITTSBURGH, July 7, 2022 – While patients with diabetes on the Medicare Advantage plan are more likely to receive preventative care, they are less likely to be prescribed new, more expensive drugs and more likely to have high blood pressure and poorer blood glucose control than patients on the Cost plan Medicare-For-Services, according to a new study led by physician-scientists at the University of Pittsburgh School of Medicine. The study, published today in Diabetes Treatment, raised the red flag that – despite increasing access to preventative care – rapid growth in Medicare Advantage registrants could signal a trend toward poorer health outcomes and gaps in care when compared to their Medicare Fee-For-Service counterparts. “Preventive care is not enough to prevent patients from utilizing the healthcare system in the future,” said lead author U...

Source/Disclosure Published by: Disclosure: Kerr reports no relevant financial disclosures. ADD TOPIC TO EMAIL ALERTS Receive emails when new articles are posted on Please provide your email address to receive emails when new articles are posted on . ” data-action=”subscribe”> Subscribe We were unable to process your request. Please try again later. If you continue to experience this problem, please contact customerservice@slakinc.com. Back to Healio Researchers identified five common themes among Indigenous patients with chronic kidney disease when exploring their relationship to health care, according to data published in international kidney. “Indigenous peoples are defined as those who first lived in an area and have distinct cultural, knowledge and linguistic traditions ...