Vly News - Professional news Platform

A team led by biologists at The University of Texas at Arlington has published a study that supports the theory that species that reproduce asexually have more harmful genetic mutations than those that use sexual reproduction. Jose Maldonado, a UTA doctoral student in biology, is the lead author of the new paper, entitled “Parthenogenesis doubles the level of amino acid substitution in whiptail mitochondria.” It was published in May in Evolution, the flagship journal of evolutionary biology. Co-authors include TJ Firneno, a postdoctoral research fellow at the University of Denver who received his Ph.D. from UTA in 2020; Alexander Hall, product application specialist at Thermo Fisher Scientific who received his Ph.D. from UTA in 2016; and Matt Fujita, UTA professor of biology, who is Maldonado’s faculty advisor and previously served in the same role for Firneno and Hall. Parthenogenesis is a natural form of asexual reproduction in which the growth and development of an embryo occur

This uncommon genetic disease was found to be caused by variations in the gene encoding the Glutamate Ionotropic Receptor AMPA Type 1 Subunit protein. A new genetic disease slows children’s brain development. A new genetic disease that causes the brains of some children to grow abnormally and delay intellectual development has been discovered by scientists. Most people with this disease, which is still so new that it doesn’t have a name, struggle with significant learning challenges that negatively impact their quality of life. Changes in the gene coding for a protein known as Glutamate Ionotropic Receptor AMPA Type Subunit 1 (GRIA1) is the underlying cause of this unusual genetic disorder, according to an international team of researchers from the universities of Portsmouth, Southampton and Copenhagen. Variant discovery will assist clinicians in developing focused treatments to assist patients and their families and will pave the way for prenatal screening and diagnosis. The GRIA1 gen

12 July 2022 12:30 Genetic defects that lead to abnormal inflammation in the hands, hips, knees, and other joints may help explain why some people are more prone to developing severe osteoarthritis than others, according to scientists from the University of Utah Health. Photo credit: Getty Images An overactive inflammatory response can trigger the most common form of arthritis A newly detected defect in a genetic signaling pathway that leads to a hyperactive inflammatory response could help explain why some people are more prone to developing severe osteoarthritis than others, according to University of Utah Health scientists. They say the discovery could eventually lead to ways to detect early onset of the disease—even before symptoms appear—and the development of new treatments for the disease. The findings, among the first to suggest that an increased inflammatory response is a major risk factor in osteoarthritis, appear in the Annals of the Rheumatic Disea

The human genome is littered with “selfish genetic elements”, which do not appear to benefit the host, but only seek to reproduce. Selfish genetic elements can wreak havoc by, for example, distorting sex ratios, impairing fertility, causing dangerous mutations, and potentially even causing population extinction. Biologists at the University of Rochester, including Amanda Larracuente, professor of biology, and Daven Presgraves, University Dean’s Professor of Biology, are using population genomics for the first time to explain the evolution and consequences of known selfish genetic elements. as Segregation Distortion ( SD ). In a paper published in the journal eLife the researchers reported that SD has led to dramatic changes in chromosomal organization and genetic diversity. Sequencing the genome first Researchers use fruit flies as model organisms to study SD , a selfish genetic element that deviates from the rules of just genetic transmission. Fruit flies share about 70 percent of