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Researchers at the University of Wisconsin-Madison have described the way enzymes and proteins interact to maintain protective coverings, called telomeres, at the ends of chromosomes, a new insight into how human cells maintain the integrity of their DNA through repeated cell division. . DNA replication is critical to sustaining life as we know it, but much of the complexity of the process — how myriad biomolecules get to where they need to be and interact through a series of intricately orchestrated steps — remains a mystery. From left, Qixiang He, Ci Ji Lim, Xiuhua Lin. “The mechanism behind how this enzyme, called Polα-primase, works has been elusive for decades,” said Ci Ji Lim, assistant professor of biochemistry and principal investigator on a new study on DNA replication published recently in Nature. “Our study provides a major breakthrough in understanding DNA synthesis at the ends of chromosomes, and generates new hypotheses about how Polα-primase – the main...

Daniel Goleman has an outspoken warning for job seekers in 2022 and beyond: It’s not enough to just be smart. Dr Goleman, an American writer and psychologist, has spent decades touting the importance of ’emotional intelligence’ in the workplace and other areas of life. And it seems that companies and organizations have caught up with him. “[In the mid-1990s] someone said to me, ‘you know, you can’t use the word emotion in a business context’. Today, it’s very, very different,” he told ABC’s RN’s Future Tense. But what exactly is emotional intelligence or EI? And is it just talking about future work or ‘must-have skills’? What is emotional intelligence? There are several definitions of emotional intelligence, but it boils down to understanding your emotions, understanding the emotions of those around you, and acting accordingly. Dr Goleman, who put the term on the map with his 1995 book, Emotional Intelligenc...

For the first time in Australian history, a trial run of a wave energy converter has succeeded in generating energy from chaotic and wild ocean waves to a power plant. Key points: Australia can now use the ocean for power generation after trials on King Island proved successful in generating energy This unit can now be commercialized and made up to five times larger and placed off any coast, anywhere in the world. Industry experts are “very happy” with the successful pilot, hope it now opens the door to the industry For years, companies around the world have tried to harness the power of the sea, with varying degrees of success. “This is truly the first project to successfully generate electricity for a customer, and it proves that ocean energy can work,” said Stephanie Thornton of the Australian Ocean Energy Group. Located off Raja Island in Bass Strait, the unit – created by Melbourne company Wave Swell Energy – has been generating electricity for t...

Laura Platt was in desperate need of money to fix her car when she saw an advert for Cigno, which resulted in a “quick loan of up to $1,000.” Key points: ASIC has banned the types of loans Cigno offers but the company appears to have prepared a new loan model Cigno made $60 million in five-and-a-half-month fees, court documents show Consumer advocates say national credit laws need updating to close legal loopholes Platt uploaded a bank statement to Cigno’s website and a few hours later $300 went into his bank account. “It was approved right away. And I didn’t really see the fine details,” Platt said. Shortly after getting his first loan with Cigno, he managed to apply for $200, because he thought he had paid off his original debt. However, Platt did not realize that his $300 loan also incurs high bookkeeping costs. He has struggled to repay the loan. Two years later, after being hit with bookkeeping and late fees, he ended up paying Cigno $2,600, of...

A subsidiary for Hyundai in the US state of Alabama has been caught using 12-year-old children to work at a factory that supplies auto parts to the Korean automaker’s assembly line. Key points: The three siblings found working in the factory were 12, 13 and 15 and did not attend school A spokesman for the Alabama Department of Labor said it would coordinate with the US Department of Labor and other agencies to investigate One former worker said there were around 50 underage workers between different factory shifts The underage staff worked at a metal stamping plant operated by SMART Alabama LLC, according to local police. SMART, listed by Hyundai in the company’s filing as a majority-owned unit, supplies parts for some of the most popular cars and SUVs made by the automaker at Montgomery, its flagship assembly plant in the US. In a statement, SMART said it follows federal, state and local laws and “denies allegations that it knowingly employs anyone who does not qualif...

Watching footage of Hurricane Katrina’s rescue at home — in fact, next door to where his mother still lives — Hulls came up with the idea of ​​a locator app. Getting funding isn’t easy – no one thought teens would own a cell phone. “That’s a good reason not to listen to investors,” he said. But he found the modal and, finally, the ASX list. Along the way, Hulls and his app have been at the center of debates about parenting style and privacy, as well as the target of social media campaigns, and even briefly, Australian tech lovers. But back to California. Hulls described the city’s tech precinct as a “ghost town”, emptied by pandemic-led remote work and sliding technology assessments. The changes are noticeable even to tourists: The Anchorage Hotel on Fisherman’s Wharf now has a concierge working from home for a week, for example. Hulls considers the sell-off in stock prices to be excessive. AFR AFR Weekend was in a meeting at ...

By mimicking the features of living systems, self-regulating lasers can produce new materials for sensing, computing, light sources and displays. While many artificial materials have advanced properties, they still have a long way to go to incorporate the versatility and functionality of living materials that can adapt to their situation. Our laser systems can reconfigure and work together, enabling the first step to emulate the ever-evolving relationship between structure and functionality that is typical of living materials. Professor Riccardo Sapienza For example, in the human body, bones and muscles are constantly rearranging their structure and composition to better support changes in weight and activity levels. Now, researchers from Imperial College London and University College London have demonstrated the first spontaneously self-organizing laser device, which can reconfigure when conditions change. The innovation, reported in Nature Physics, will help enable the development o...

Producing biomaterials that match the performance of cartilage and tendons has been a elusive goal for scientists, but new materials created at Cornell represent a promising new approach to mimic natural tissue. The results are published July 8 in the Proceedings of the National Academy of Sciences, and provide a new strategy for synthesizing clinical solutions for damaged tissue. The tissue must be soft enough to bend and flex, but durable enough to withstand prolonged loads – for example, the loads that the knee tendons have to support. When tissues are worn or damaged, collagen hydrogels and synthetic materials have the potential to serve as substitutes, but they do not have the right combination of biological and mechanical properties of natural tissues. Now, Cornell researchers have engineered a biohybrid composite material with essential characteristics of natural tissue. It consists of two main ingredients: collagen – which provides softness and biocompatibility to the materia...

On the eve of the birth of her first son, 33-year-old Kristy O’Brien thought her career would take a hit. I think I’ll do some shit work on both [work and parenting], I will step down in my career; accepted some mediocre positions working around children,” said the journalist for ABC Rural. The last thing Darwinians hope for a few months after maternity leave is to be offered the show of their dreams; traveled around Australia to film the first season of Movin’ to the Country. “I told my family: ‘I need to do this. I really want to,'” Kristy said. “I don’t want to lose my career which is part of my identity.” So he took five-month-old Hudson on the road with him. Since then, Kristy has been shooting season two while pregnant with her son Nash, who was born 10 weeks ago. We talked to working moms about the challenges of getting work done with a baby in tow—and why it’s all worth it. Challenging moments that he will alway...

It said it was expected to “resul in a substantial increase in infections, hospitalizations and unfortunately, deaths, at a time when our communities and health systems are already under stress”. Among measures including increasing vaccination rates, the group advised employers to review their occupational health and safety risks and “consider the appropriateness of some employees working from home and supporting employees to take time off when sick”. Major wholesale retailers including Coles said they were prepared for any increase in COVID-19 numbers. Credit: Paul Jeffers The advice comes amid a sharp increase in cases. Victoria recorded 7934 new cases of coronavirus on Sunday, while New South Wales reached 8670 new cases. There are more than 300,000 active cases across the country and hundreds of people die of COVID-19 every week. Governments across the country are wary of reintroducing the mandate, insisting the country is in a new phase of the pandemic and...