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Washington [US]July 10 (ANI): Researchers have definitively linked the function of a protein-specific domain important in plant microbial biology to cancer triggers in humans, knowledge that has eluded scientists for decades. The team’s findings, published in Nature Communications Biology, open new avenues for the development of selective drug therapies to fight different types of cancers such as cancers that start in the breast and stomach. Read Also | Women With Anorexia Likely To Have Underweight Babies, Study Says. ORNL scientists set out to experimentally prove what they first concluded with computational studies: that the plasminogen-apple-nematode domain, or PAN, is associated with cell proliferation that promotes tumor growth in humans and defense signaling during plant-microbial interactions in bioenergetic plants. This association was first made when researchers were exploring the genomes of plants such as poplars and willows. In the latest study, the ORNL team demonstrated

Exercise-based physical therapy remains in no way inferior to arthroscopic partial meniscectomy for treating degenerative meniscal tears, according to long-term data from the ESCAPE trial, suggesting physical therapy to be the preferred treatment over surgery. At the 5-year mark, the patient’s reported knee function after 16 sessions of physical therapy was not lower than that observed after surgery, with a between-group difference of 3.5 points on the International Knee Documentation Committee Subjective Form 100 points (95% CI 0.7-6). ,3, P <0.001 for noninferiority) in the intention-to-treat analysis, according to movement scientist Julia Noorduyn, MSc, of OLVG Amsterdam, The Netherlands, and colleagues. For the surgery and exercise therapy groups, respectively, the mean improvement from baseline was 29.6 and 25.1 points at 5 years. The progression of knee osteoarthritis, assessed radiographically, was equally low between the two groups, Noorduyn’s team reported in JAMA Network