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A team led by the University of Minnesota Twin Cities has developed a new technique to image mRNA molecules in the brains of live mice. By genetically modifying the mice to produce mRNA labeled with the green fluorescent protein (shown above), the researchers were able to see when and where the mouse brain produced Arc mRNA. Credit: Hye Yoon Park, University of Minnesota’s Twin Cities A team led by the University of Minnesota’s Twin Cities has developed a new technique that allows scientists and engineers, for the first time, to visualize mRNA molecules in the brains of living mice. This research reveals new insights into how memories are formed and stored in the brain and could provide scientists with new information about diseases like Alzheimer’s. This paper was published in Proceedings of the National Academy of Sciences (PNAS) . There are still many mysteries surrounding the ...

A team led by the University of Minnesota’s Twin Cities has developed a new technique that allows scientists and engineers, for the first time, to visualize mRNA molecules in the brains of living mice. This research reveals new insights into how memories are formed and stored in the brain and could provide scientists with new information about diseases like Alzheimer’s. The paper is published in the Proceedings of the National Academy of Sciences of the United States of America (PNAS), a peer-reviewed, multidisciplinary, high-impact scientific journal. There are still many mysteries surrounding the process of how memories are physically created and stored in the brain. It is well known that mRNA—a type of RNA involved in making proteins—is produced during the processes of memory formation and storage, but the technology for studying this process at the cellular level is still limited. Previous research has often involved dissecting mice to examine their brains. A research...